Research Paper Volume 16, Issue 5 pp 4469—4502

Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8

class="figure-viewer-img"

Figure 12. Genomic mutation differences among model groups. (A) Waterfall plot of the top 30 genes (mutation frequency) with SNV in high-risk group; (B) Waterfall plot of the top 30 genes (mutation frequency) with SNV in low-risk group; (CF) Cumulative distribution histogram of frequently mutated genes with significant differences between high and low-risk groups; (G) Survival curve showing the difference between mutant and wild-type groups of gene TP53; (H) Box plot showing the difference in TMB between high and low-risk groups; (I) KM survival curve showing the difference between high and low TMB groups, with red representing high TMB group and blue representing low TMB group.