Research Paper Volume 16, Issue 5 pp 4378—4395

The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma

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Figure 8. Knockdown of UBA2 inhibited the proliferation, invasion and migration of LUAD cells. (A) The UBA2 expression was measured by quantitative RT-PCR after transfecting UBA2-shRNAs in A549 and H1299. (B, C) The proliferative capacities of (B) H1299 and (C) A549 cells were measured by CCK8. (D) The migrative capacities of A549 and H1299 cells were measured by wound healing assay. (E) The invasive capacities of A549 and H1299 cells were measured by transwell assays. *p < 0.05, **p < 0.01 ***p < 0.001.