Research Paper Volume 16, Issue 5 pp 4363—4377
Probucol protects against brain damage caused by intra-neural pyroptosis in rats with vascular dementia through inhibition of the Syk/Ros pathway
Figure 5. Probucol attenuates CCH-induced microglial apoptosis in rats and BV2 cells treated with LO/LG. (A) WB assay of apoptosis markers (Caspase-3, Bax, and Bcl-2). (B) Statistical data of WB assay results. n = 12/group. (C) Number of apoptotic cells measured by flow cytometry. n = 3/group. Data are expressed as mean ± SEM. n = 12/group. *P < 0.05 and **P < 0.01: CCH group vs. Probucol group.