Research Paper Volume 16, Issue 5 pp 4224—4235
The effect of STAT1, miR-99b, and MAP2K1 in alcoholic liver disease (ALD) mouse model and hepatocyte
Figure 6. STAT1/miR-99b/MAP2K1 axis regulates apoptosis of AML-12 cells. (A) The AML-12 cells were transfected with STAT1 overexpressing plasmid and the expression of MAP2K1 was determined in the cells. (B) The apoptosis was analyzed in AML-12 cells treated with EtOH, or cotreated with EtOH and miR-99b mimic or MAP2K1 overexpressing plasmid. (C) A hypothesis model of this study was shown. *P < 0.05, **P < 0.01.