Research Paper Volume 16, Issue 5 pp 4224—4235
The effect of STAT1, miR-99b, and MAP2K1 in alcoholic liver disease (ALD) mouse model and hepatocyte
Figure 2. STAT1 is found as an upstream factor of miR-99b by microarray analysis in ALD mouse model. (A) The microarray analysis was performed in ALD mice. The mRNA heatmap was shown. The overlap was performed using microarray analysis and TransmiR v2.0 database. (B) The expression of STAT1 was measured by qPCR in ALD mice. (C) The expression of STAT1 was measured by qPCR in AML-12 cells treated with 100 mM EtOH. (D) The correlation of STAT1 with ALT levels was analyzed in ALD mice. *P < 0.05.