Research Paper Volume 16, Issue 5 pp 4224—4235
The effect of STAT1, miR-99b, and MAP2K1 in alcoholic liver disease (ALD) mouse model and hepatocyte
Figure 1. The upregulation of miR-99b is identified by microarray analysis in ALD mouse model. (A, B) The microarray analysis was performed in ALD mice. The miRNA heatmap (A) and WGCNA (B) were shown. (C) The expression of miR-99b was detected by qPCR in ALD mice. (D) The expression of miR-99b was measured by qPCR in AML-12 cells treated with 100 mM EtOH. (E) The correlation of miR-99b with ALT levels was analyzed in ALD mice. (F) The serum AST level. *P < 0.05.