Research Paper Volume 16, Issue 4 pp 3973—3988
MicroRNA-320a enhances LRWD1 expression through the AGO2/FXR1-dependent pathway to affect cell behaviors and the oxidative stress response in human testicular embryonic carcinoma cells
Figure 5. Overexpression of AGO2 and FXR1 enhanced the miR-320a-mediated increase in LRWD1 protein expression. Western blotting was performed to determine the protein expression of LRWD1 in cells overexpressing (A) FXR1 and (B) AGO2 in the presence or absence of the miR-320a mimic and inhibitor. Quantitative analysis of LRWD1 protein expression modified by (C) FXR1 and (D) AGO2 overexpression showed the significance of the regulatory effect of the miR-320a mimic and inhibitor (*p < 0.05, **p < 0.01, ***p < 0.001 compared with the negative control).