Research Paper Volume 16, Issue 4 pp 3803—3822

Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis

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Figure 1. Construction of WGCNA co–expression network in training set. (A) The investigation involved the utilization of scale-free fit index and mean connectivity analysis across various soft-thresholding powers. (B) To identify and establish connections between related modules, the clustered dendrograms were truncated at 0.25 heights. (C) The WGCNA modules were assigned and represented by a colored horizontal bar in the cluster dendrograms. (D) The module feature genes were analyzed for collinearity and presented in a heatmap, where red indicates high correlation and blue indicates low correlation. (E) The topological overlap matrix (TOM) for each module was visualized in a WGCNA network heatmap. (F) Module-trait correlations. Positive correlations are represented by red and negative correlations by blue.