Figure 4 — Yangyinghuoxue decoction exerts a treatment effect on hepatic fibrosis by PI3K/AKT pathway in rat model: based on the network pharmacology and molecular docking

Research Paper|Volume 16, Issue 4|pp. 3773–3789

Yangyinghuoxue decoction exerts a treatment effect on hepatic fibrosis by PI3K/AKT pathway in rat model: based on the network pharmacology and molecular docking

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Figure 4.(A) Antioxidant levels in the treatment group YYHXD. GSH, SOD, MDA. (B, C) YYHXD can attenuate the apoptosis of liver parenchymal cells induced by CCl4 liver fibrosis, ^**P < 0.01 compared with the model group. The result of TUNEL assay was shown in Figure 4B, 4C. The apoptosis rate in YYHXD group and colchicine group decreased significantly, ^****P < 0.0001 compared with the model group.