Research Paper Volume 16, Issue 4 pp 3750—3762
Suppression of cerebral ischemia injury induced blood brain barrier breakdown by dexmedetomidine via promoting CCN1
Figure 2. Dex suppressed cerebral ischemia injury and increased tight junction protein expression. (A) TTC staining was performed to study the infarct ratio; (B) Evans blue staining was conducted to investigate blood brain barrier injury; (C) The levels of IL-6, IL-1β, and TNF-α in serum were detected; (D) The expression levels of tight junction proteins were determined in brain tissues. *p <0.05. n = 5.