Research Paper Volume 16, Issue 4 pp 3531—3553

Senescence-related genes analysis in breast cancer reveals the immune microenvironment and implications for immunotherapy

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Figure 7. Immunotherapy response analysis. (A) A heatmap was drawn to illustrate the relationship between immune cell expression and stromal score, immune score, estimate score, and tumor purity. Immune cell expressions were lower in the high-risk group. (B) The stromal score was lower in the high-risk group than in the low-risk group (P<0.001). (C) The immune score was lower in the high-risk group than in the low-risk group (P<0.001). (D) The ESTIMATE score was lower in the high-risk group than in the low-risk group (P<0.001). (E) Patients in the high-risk group had higher tumor purity scores than those in the low-risk group (P<0.001). (FI) The low-risk subtype has significantly greater IPS.