Research Paper Volume 16, Issue 4 pp 3420—3530

Insights into serum metabolic biomarkers for early detection of incident diabetic kidney disease in Chinese patients with type 2 diabetes by random forest

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Figure 2. KEGG pathway analysis of all SAMs. (A) An overview view of pathway analysis; (B) Table of the matched pathway with p-values from pathway enrichment analysis and pathway impact values from the pathway topology analysis using MetaboAnalyst 4.0 and KEGG database (Hits ≥ 2); (C, D) Simplified pathways of tryptophan metabolism and phenylalanine metabolism with the change trends of metabolites and their ratios at Stage 4 compared with the normal group.