Research Paper Volume 16, Issue 4 pp 3404—3419
Orexin-A alleviates ferroptosis by activating the Nrf2/HO-1 signaling pathway in traumatic brain injury
Figure 4. Changes in markers related to ferroptosis following OXA treatment. (A) Expression of GPX4, SLC7A11, and PTGS2 in injured peripheral cortex of rats following TBI was found via western blotting. (B–D) Western blot quantitative data for different groups. (E–G) Relative mRNA levels of GPX4, SLC7A11, and PTGS2 in injured peripheral cortex of rats in each group 24 hours after TBI. Findings are shown as mean ± standard deviation. *P < 0.05, **P < 0.01, ***P < 0.001.