Research Paper Volume 16, Issue 4 pp 3404—3419
Orexin-A alleviates ferroptosis by activating the Nrf2/HO-1 signaling pathway in traumatic brain injury
Figure 2. The effect of OXA on the sham group rats and the effect of ML385 on OXA. (A–C) The protein expression levels of GPX4 and SLC7A11 in sham group rats after intervention with OXA. (D–F) Comparison of the effects of OXA and Lip-1 on ferroptosis -related proteins SLC7A11 and PTGS2. (G) Typical HE staining images: comparison of the protective effects of OXA and Lip-1 on the brain. Statistical data are shown in mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001.