Research Paper Volume 16, Issue 4 pp 3363—3385

Figure 3. NUDT21 has been linked to genomic instability in cancer. (A) Genomic alterations of NUDT21 in TCGA pan-cancer were analyzed, including mutations, amplifications and deep deletions. (B) Landscape of SNV of NUDT21 in pan-cancer containing missense mutations, shift deletions and splice sites. (C) Kaplan-Meier plots using the TIDE web tool to show the prognostic significance of CNVs of NUDT21 in eight cancers. (D) Radar plot showing the association between TMB (top), MSI (bottom) and NUDT21 in patients with pan-cancer; dashed circles indicate a correlation coefficient of 0, and the intersection of solid lines (red or blue) inside the dashed circle indicates a negative correlation coefficient, and outside the circle indicates a positive correlation coefficient. (E) Bar graph showing the expression coefficients between HRD or ploidy and NUDT21 expression. (F) Bar graph shows the association between NUDT21 expression and neoantigen counts in pan-cancer.