Research Paper Volume 16, Issue 3 pp 2908—2933
Anoikis-related gene signature is associated with immune infiltration and predicts the prognosis of non-small cell lung cancer
Figure 2. Construction of prognostic model in the TCGA NSCLC cohort. (A) The LASSO coefficient profiles were constructed using the 33 anoikis-related genes, and the tuning parameter (λ) was calculated based on the minimum criteria for OS with ten-fold cross validation. Five genes were selected according to the best fit profile. (B) Univariable analyses of the expression values of the five genes with overall survival in the TCGA NSCLC cohort. (C) Distributions of ARGRS, survival status of NSCLC patients, and expression profiles of the gene signatures. (D) Survival analysis showing the prognostic value of ARGRS in the TCGA NSCLC cohort. (E) Heatmap showing the distribution of clinicopathologic features between ARGRS-high and low groups. (F) Comparison of ARGRS among different clinicopathologic features.