Research Paper Volume 16, Issue 3 pp 2774—2788

Machine learning-based B cell-related diagnostic biomarker signature and molecular subtypes characteristic of ulcerative colitis

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Figure 1. Identification the immune cell subtype related gene module for UC via WGCNA. (A) Identification of the optimal soft threshold (β) to develop the WGCNA. (B) Clustering of each gene module. (C) Correlation evaluation of each gene module. (D) Generation of the unique gene module via dynamic tree cut. (E) Correlation analysis of each gene module and 23 immune cell subtypes. (F) Relationship of module membership in yellow module and gene significance.