Review Volume 16, Issue 3 pp 3021—3042

Role of estrogen in treatment of female depression

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Figure 3. Relationship between estrogen and neuroinflammation in depression. Abbreviations: GPER: G protein-coupled estrogen receptor; ER: estrogen receptor; ERK: extracellular signal-regulated kinase; NF-κB P65: nuclear factor kappa-B P65; TLR4: toll-like receptor 4; MyD88.