Research Paper Volume 16, Issue 3 pp 2340—2361
5-methylcytosine RNA modification regulators-based patterns and features of immune microenvironment in acute myeloid leukemia
Figure 6. Consensus clustering and prognostic model of m5C regulators in acute myeloid leukemia (AML). (A) Consensus clustering matrix for k = 2. (B) Box plots showing the expression of m5C regulators in two clusters. (C, D) LASSO Cox regression algorithm was used for calculating the minimum criteria. (E) Kaplan–Meier curves showing the overall survival of AML patients with high- and low-risk scores. (F) ROC curve showing the AUC value of the model for different survival times. (G, H) Distribution of the risk score and survival status. (I) Box plots showing the expression of m5C regulators in high- and low-risk groups. (J) Heatmap and clinicopathological characteristics of AML molecular subtypes and high- and low-risk groups. *p < 0.05, **p < 0.01, ***p < 0.001.