Research Paper Volume 16, Issue 2 pp 1968—1979

The role of miR-6884-5p in epithelial-mesenchymal transition in non-small cell lung cancer

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Figure 1. The expressions of miR-6884-5p and S100A16 in non-small cell lung cancer tissues. (A) qRT-PCR was used to determine the expressions of miR-6884-5p between adjacent tissues and NSCLC tissues (n = 92 for each). (B) ROC analysis of the expressions of miR-6884-5p for the diagnosis of NSCLC. (C) Comparison of the expressions of miR-6884-5p between tumor invasion of T1-T2 (n = 68) and T3-T4 (n = 24). (D) Comparison of the expressions of miR-6884-5p between TNM stage of I-II (n = 53) and III-IV (n = 39). (E) qRT-PCR was used to determine the mRNA expressions of S100A16 between adjacent tissues and NSCLC tissues (n = 92 for each). Violin plot was used to show the data. *p < 0.05, **p < 0.01, ***p < 0.001 from unpaired t-test with Welch’s correction. (F) Pearson correlation coefficient analysis was employed to analyze the correlations of the expressions of miR-6884-5p and the mRNA expressions of S100A16 in NSCLC tissues (n = 92).