Research Paper Volume 16, Issue 2 pp 1938—1951
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer
Figure 7. Elevating lncMEG3 inhibits PCa proliferation and promotes apoptosis in vivo. (A) Images of the tumors in the subcutaneous mouse model. (B) Images of subcutaneous tumors formed by the PC3 cells. (C, D) Growth curves and weight analyses of subcutaneous tumors formed by PC3 cells, * P < 0.05. (E) H&E staining revealed that the tumor cells in the LV-lnc group were loosely arranged and had less vascular compared with the control group, scale bar 20 μm. (F) IHC staining of tumor in situ showed the difference between the LV-lnc group and LV-control group, scale bar 20 μm. (G) Western blot of proteins changed in tumor tissues.