Research Paper Volume 16, Issue 6 pp 5027—5037

Phoenixin 20 ameliorates pulmonary arterial hypertension via inhibiting inflammation and oxidative stress

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Figure 6. PHN-20 inhibited the NLRP3 signaling and increased SIRT1 expression in hypoxia-treated PMECs. (A) Western blots of NLRP3, ASC, and SIRT1; (B) Analysis of the blots. (**, P<0.01 vs. control group; #, ##, P<0.05, 0.01 vs. hypoxia group).