Research Paper Volume 16, Issue 2 pp 1897—1910
Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript
Figure 6. Knockdown of IMP3 reverses E2F5-induced cellular phenotypes in OSCC cells. (A, B) qRT-PCR and Western blot were performed to determine the impact of OSCC cells treated with E2F5 plus siIMP3 expression vectors or related negative control. (C) The growth of OSCC cells were detected using CCK8 assay. Relative expression levels were calculated using the image J software (n = 6). P ≤ 0.05 was considered to be statistically significant, *P < 0.05, **P < 0.01, ***P < 0.001.