Research Paper Volume 16, Issue 2 pp 1879—1896

CDK16 as a potential prognostic biomarker correlated with an immunosuppressive tumor microenvironment and benefits in enhancing the effectiveness of immunotherapy in human cancers

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Figure 7. The relationship between CDK16 and the regulation of the tumour microenvironment. (A) Heatmap represents the correlation between CDK16 expression and TME scores in pan-cancer. (B) The relationship between CDK16 and the tumour microenvironment. (C) After H1299 cells were transfected with si-CDK16, the level of CDK16 was evaluated by qRT-PCR. (D) The cell viability of cells was examined by CCK-8 assay. Red represents positive correlation, blue represents negative correlation, and the darker the color, the stronger the correlation. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.