Research Paper Volume 16, Issue 2 pp 1781—1795
Identification of key ferroptosis genes and mechanisms associated with breast cancer using bioinformatics, machine learning, and experimental validation
Figure 1. Identification of ferroptosis-related DEGs in breast cancer. (A) Volcano plot of all DEGs between tumor (BC group, n = 1091) and adjacent tissues (NC group, n = 113). Red and blue dots represent significantly upregulated and downregulated genes, respectively. (B) Venn diagram showing the overlap between ferroptosis-related genes and DEGs. (C) Heatmap of differentially expressed ferroptosis-related genes in tumor (BC group, n = 1091) and adjacent tissues (NC group, n = 113). The color scale represents the relative expression level of each gene, with red indicating high expression and green indicating low expression.