Research Paper Volume 16, Issue 2 pp 1767—1780
Tremella fuciformis polysaccharides induce ferroptosis in Epstein–Barr virus-associated gastric cancer by inactivating NRF2/HO-1 signaling
Figure 2. TFP decreased EBV-infected AGS and MKN45 cell viability in a dose- and time-dependent manner. EBV-infected AGS and MKN45 cells were treated with 0, 5, 10, 25, 50, 100, or 200 μg/mL TFP or 0, 1, 2, 4, 6, 8, 16, 32, or 64 μg/mL TFP for 24 h. CCK-8 assays showed that TFP significantly decreased AGS (A) and MKN45 (B) cell viability. EBV-infected AGS and MKN45 cells were treated with 40 μg/mL and 20 μg/mL TFP for 12 h, 24 h, 48 h and 72 h. CCK-8 assays demonstrated that TFP decreased AGS (C) and MKN45 (D) cell viability in a time-dependent manner. ***p<0.001 vs. con.