Research Paper Volume 16, Issue 2 pp 1536—1554

Prognostic characteristics of a six-gene signature based on ssGSEA in sarcoma

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Figure 9. An analysis of six hub genes for drug sensitivity. Drug susceptibility to Abiraterone and Zoledronate was positively correlated with VEGFA expression, while Fludarabine, Cytarabine, Cladribine, and Vorinostat were negatively correlated. Drug susceptibility to Tamoxifen, Vinorelbine, Tyrothricin, Depsipeptide, Actinomycin, Mithramycin, and Carfilzomib was negatively correlated with NETO2 expression. Drug sensitivity to Acrichine and 6-Thioguanine was positively correlated with RCC1 expression. A negative correlation was found between Selumetinib sensitivity and BIRC5 expression. Abbreviation: Cor: correlation coefficient.