Research Paper Volume 16, Issue 2 pp 1374—1389
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis
Figure 8. Experiment design. The APP/PS1 mice were divided into a serene group and an exercise group, and the C57BL/6 mice were used as the control. The exercise group was exercised by treadmill for 12 weeks, with the speed increasing from 7 m/min to 14 m/min from weeks 1 to 8 and remaining constant at 15 m/min from 9 to 12 weeks. Exercise was performed 5 days per week for 45 min each time.