Research Paper Volume 16, Issue 2 pp 1374—1389
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis
Figure 6. Mouse intestinal barrier and LPS displacement. (A) Representative images and length statistics of the animals’ colons (n = 12 per group). (B) Representative images of the colon HE staining (n = 4 per group). (C) Representative images of the intestinal ZO-1 and occludin immunofluorescence (n = 4 per group). (D) Quantitative statistics of the occludin fluorescence area. (E) Quantitative statistics of the ZO-1 fluorescence area. (F) LPS contents in serum samples (n = 6 per group). (G) LPS contents in the animals’ brains (n = 4 per group). The data are expressed as means ± SDs. # p < 0.05 and ## p < 0.01 compared with the WT group, and * p < 0.05 and ** p < 0.01 compared with the SE-AD group.