Research Paper Volume 16, Issue 1 pp 928—947

Mechanism of lysine oxidase-like 1 promoting synovial inflammation mediating rheumatoid arthritis development

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Figure 7. LOXL1 expression in human RA synovial membrane. (A) Expression of LOXL1, TNF-α, IL-6, INOS and COX2 was detected in RA synovium, OA synovium and normal synovium by qPCR. (B) LOXL1, INOS and COX2 protein expression level was assessed in RA synovium, OA synovium and normal synovium using western blot. (C) Quantitative analysis of western blot results. (D) HE staining of RA synovium, OA synovium and normal synovium. Low magnification scale bar = 200 μm and High magnification scale bar = 50 μm. *P < 0.05, **P < 0.01, ***P < 0.001.