Research Paper Volume 16, Issue 2 pp 1318—1335

Figure 2. Expression of lncRNA MEG3, and CNN1 in breast cancer tissues and cells. (A) qRT-PCR detected the expression of lncRNA MEG3, miR-330, and CNN1 in tumor and normal tissue of our cohort. ^*P < 0.05, ^**P < 0.01 vs. para-tumor tissue (Normal). (B) mRNA expression of miR-330, lncRNA MEG3, and CNN1 in MCF10A, MCF-7, BT-474, and MDA-MB-468 cells. ^*P < 0.05, ^**P < 0.01 vs. MCF10A cells. (C) Subcellular location of lncRNA MEG3 in MCF-7 and BT-474 cells. (D) lncRNA MEG3 was overexpressed in MCF-7 and BT-474 cells. lncRNA MEG3 expression was detected by qRT-PCR. ^**P < 0.01 vs. Blank, ^##P < 0.01 vs. lncRNA NC. Abbreviations: NC: negative control; OE: overexpression.