Research Paper Volume 16, Issue 1 pp 779—798

SPC25 as a novel therapeutic and prognostic biomarker and its association with glycolysis, ferroptosis and ceRNA in lung adenocarcinoma

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Figure 7. Association between SPC25 and ferroptosis-related genes. (A) The correlation between SPC25 expression and 25 ferroptosis-related genes was analyzed in the TCGA LUAD dataset and GSE31210 dataset. (B, C) The differential expression of 25 ferroptosis-related genes between the high and low SPC25 expression groups was analyzed in the TCGA LUAD dataset and GSE31210 dataset. (D) Prognostic analysis of 25 ferroptosis-related genes was conducted in the TCGA LUAD dataset. (E) The Veen plot displays the intersection of genes with statistically significant differences in the aforementioned analyses. (***p < 0.001; **p < 0.01; *p < 0.05; Abbreviation: ns: not significant).