Research Paper Volume 16, Issue 1 pp 779—798
SPC25 as a novel therapeutic and prognostic biomarker and its association with glycolysis, ferroptosis and ceRNA in lung adenocarcinoma
Figure 4. Cell cycle regulation by SPC25 in LUAD. (A, B) Flow cytometry analysis revealed that compared to the control group, the experimental group exhibited an increase in the percentage of cells in the S and G2/M phases, accompanied by a decrease in the percentage of cells in the G0/G1 phase, leading to cell cycle arrest at the G2/M and S phases. (C–E) We utilized lollipop plots to illustrate the correlations between SPC25 and key genes including cyclins, CDKs, and CDKIs in the TCGA LUAD dataset. (***p < 0.001; **p < 0.01; *p < 0.05; Abbreviation: ns: not significant).