Research Paper Volume 15, Issue 24 pp 15557—15577

Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation

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Figure 10. Effect of Aloin A on body weight, muscle quality and adipose mass in mice bearing lung tumor. (A) The tumor free body weight to initial body weight (IBW) ratio. (B) Gastrocnemius muscle to initial body weight (IBW) ratio. (C) Quadriceps to initial body weight (IBW) ratio. (D) Tibialis anterior muscle to initial body weight (IBW) ratio. (E) Soleus to initial body weight (IBW) ratio. (F) Epididymis fat mass. The values are shown as the mean ± SEM (n = 8). **P < 0.01, ***P < 0.001 vs. the control group. #P < 0.05 vs. the LLC group.