Figure 1. Differentially expressed genes and hub genes. (A) Volcano plot of 434 ARGs in GSE16088 and GSE28425 datasets. (B) Heatmap of DEGs in GSE16088 and GSE28425 datasets. (C) Protein-protein interaction (PPI) network of 71 DEGs and the critical module. Identifying the first 10 ARGs and constructing the corresponding PPI network using the degree (D) and betweenness (E) topological method. (F) Venn calculation is applied to identify seven hub ARGs.