Research Paper Volume 16, Issue 2 pp 1249—1275

Figure 4. Identification of disulfidptosis-related clusters in ccRCC. (A) A color-coded heat map of the consensus matrix for k = 3. (B) Cumulative distribution function (CDF) curve of unsupervised clustering when k = 2–9. (C) Relative change in area under the CDF curve when k = 2–9. (D) Principal component analysis shows notable differences in the transcriptome among the three disulfidptosis clusters. (E) Kaplan–Meier survival curves corresponding to the various disulfidptosis clusters. (F) A heat map of disulfidptosis-related molecules and clinicopathological features of patients in the three disulfidptosis clusters. (G) The expression of the ten disulfidptosis-related molecules in the three disulfidptosis clusters. (H) The abundance of 28 types of infiltrating immune cells in the three disulfidptosis clusters. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. Abbreviation: ns: no significant.