Research Paper Volume 15, Issue 24 pp 14553—14573

Systemic changes induced by autologous stem cell ovarian transplant in plasma proteome of women with impaired ovarian reserves

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Figure 4. Comparative assessment of the proteomic effects of stem cell mobilization and injection in patients with poor ovarian response (POR) and premature ovarian insufficiency (POI). (A) Venn diagram (left) and protein name (right) of the differentially expressed proteins in APHERESIS samples of patients with POR and POI (both study arms), showing the relationships between the type of protein regulation (up/down). (B) Venn diagram (left) and protein name (right) of the differentially expressed proteins three months after autologous stem cell ovarian transplantation (ASCOT) in patients with POR and patients with POI from the ASCOT arm, showing the relationships between the type of protein regulation (up/down). The total number of significant differentially expressed proteins in each category is represented in brackets.