Research Paper Volume 16, Issue 1 pp 593—616
Integrated multi-omics analyses reveal the TM4SF family genes with prognostic and therapeutic relevance in hepatocellular carcinoma
Figure 11. TM4SFs regulate tumor growth and stemness maintenance of CSCs in LIHC. (A) The levels of TM4SF4 transfection with shRNA were analyzed by WB. (B) Colony formation assays showed that knockdown of TM4SF4 inhibited CRC cell growth. (C) Sphere formation analysis suggested that the downregulation of TM4SF4 could significantly inhibit the sphere formation capacity. *p < 0.05, **p < 0.01, ***p < 0.001.