Research Paper Volume 15, Issue 23 pp 13628—13645

Figure 3. Effect of donor age on success of resolving acute DNA damage. (A) Plots showing all individual cells of representative young, middle, and older donors. (B) The percentage of cells with high levels of DNA damage (>60% of DNA in comet tails) for each donor, with bars showing the mean ± SEM of all donors per age group. (C) Same as B except now showing the percentage of cells with low levels of DNA damage (<15% of DNA in comet tail). For B and C the repair time, age, and their interaction were significant sources of variation by 2-way repeated measures ANOVA. Significant differences between groups at each time point (Tukey’s multiple comparisons test, p < 0.05) are denoted by symbols: (^*) = young vs. middle, (^#) = young vs. older, (^&) = middle vs. older.