Research Paper Volume 16, Issue 2 pp 1096—1110
TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage
Figure 6. Effect of calcium on TRPV1 mediated NLRP3 inflammasome activation. (A) The calcium content of BV2 cells was assessed at 24 h after modeling. (B–E) The relative protein expression of NLRP3, ASC, and caspase-1 p20 in BV2 cells at 24 h post modeling was assessed via western blot. (F) The protein level of IL-1β in BV2 cells supernatant at 24 h post modeling was assessed via ELISA. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001.