Research Paper Volume 16, Issue 1 pp 348—366

Figure 4. Single cell RNA sequencing analysis of the relationship between SNRPB and cell cycle, oxidative stress and ferroptosis in HCC. (A) t-SNE dimensionality reduction of the SNRPB expression levels in HCC samples. (B) HCC cells were divided into high expression of SNRPB subset (HCC_SNRPB_High) and low expression of SNRPB subset (HCC_SNRPB_Low). (C) Analysis of SNRPB expression between HCC_SNRPB_High and HCC_SNRPB_Low groups. (D, E) Relationship between HCC stages and the expression level of SNRPB in HCC_SNRPB_High and HCC_SNRPB_Low groups. (F–H) The expression levels of cell cycle, oxidative stress, and ferroptosis-related genes in HCC_SNRPB_High and HCC_SNRPB_Low groups. The size of the dots represents the percent of expressed cells, and the color from red to blue represents the average expression level from high to low. (I) GO enrichment analysis of HCC_SNRPB_High and HCC_SNRPB_Low groups. (J) KEGG enrichment analysis of HCC_SNRPB_High and HCC_SNRPB_Low groups. (K–M) ssGSEA scores of cell cycle, oxidative stress, and ferroptosis-related pathways in HCC_SNRPB_High and HCC_SNRPB_Low groups.