Research Paper Volume 16, Issue 1 pp 322—347

Clinical significance and immune characteristics analysis of miR-221-3p and its key target genes related to epithelial-mesenchymal transition in breast cancer

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Figure 1. MiR-221-3p differential expression in BC and normal adjacent tissues based on TCGA database (A) and validated by the GSE45666 dataset (B) and cell lines (C). The clinical significance of miR-221-3p expression (D). ROC curve shows the discriminative power of miR-221-3p between the Basal-like subtype and others (E). In the present study, NS indicates no statistical difference, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.