Research Paper Volume 15, Issue 24 pp 15419—15433
Clinical value of SLC12A9 for diagnosis and prognosis in colorectal cancer
Figure 4. Prognostic and clinical correlation analysis of SLC12A9 gene. (A) Survival analysis showed that high expression of SLC12A9 was associated with poor prognosis in colorectal cancer. (B–D) There were no significant abnormalities in SLC12A9 expression based on gender, age, and T stage of the patients. (E–H) SLC12A9 expression was up-regulated in patients with N1&N2 compared to N0 patients (p < 0.01). Additionally, the expression of SLC12A9 was elevated in M1 patients compared to M0 patients (p < 0.05). Moreover, SLC12A9 expression was higher in patients with lymph node metastasis compared to those without, and it was also higher in Stage III and Stage IV patients compared to Stage II patients (p < 0.05).