Research Paper Volume 15, Issue 24 pp 15382—15401

Figure 2. Expression of marker proteins in healthy people. (A) Immunofluorescence images showed decreased SPC in lung tissue of the elderly. (B) Immunofluorescence images showed increased α-SMA expression in aging human lung tissue than in young. (C) Double immunofluorescence staining showed that the expression of S100A4 and P16 were significantly higher in aged human lung tissues than in young lung tissues. (D) Double immunofluorescence staining showed that P16 increased in the old and decreased in the young. E-cadherin decreased in the old and increased in the young.