Research Paper Volume 15, Issue 24 pp 15360—15381

Clinical and therapeutical significances of the cluster and signature based on oxidative stress for osteosarcoma

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Figure 1. Characteristics of OXS-clusters in TARGET-OS. (A) Forest plot for Univariate Cox regression analysis of ten prognostic OXRGs; (B) Cluster diagram for subtype analysis of osteosarcoma samples, with the intragroup correlations being the highest and the inter-group correlations being low when k=2; (C) Kaplan-Meier curve of the correlation between OXS-clusters and survival status of osteosarcoma patients; The green curve denotes OS-cluster1, and the purple curve denotes OS-cluster2. (D) The heatmap displaying the distribution of the ten prognostic OXRGs, clinicopathological characteristics (Sex, Age) and OXS-clusters; Purple represents high gene expression, while green represents low gene expression.