Research Paper Volume 15, Issue 24 pp 15228—15242
Causal effects of lipid-lowering therapies on aging-related outcomes and risk of cancers: a drug-target Mendelian randomization study
Figure 3. Causal effects of the genetically proxied lipid-lowering drug targets on age-related noncancerous diseases. The forest plot showed the estimated effects of 1 mmol/L lower LDL-C or TG concentration by target-specific variants in each drug target gene on age-related noncancerous diseases, using the IVW method. OR and 95% CI indicated the effect estimates of a 1mmol/L change of circulating lipids on outcomes.