Research Paper Volume 15, Issue 24 pp 15084—15113
Copper metabolism-related risk score identifies hepatocellular carcinoma subtypes and SLC27A5 as a potential regulator of cuproptosis
Figure 9. SLC27A5 upregulates FDX1 in HCC. (A, B) The correlation between the expression of SLC27A5 and that of FDX1 in TCGA-LIHC (A) and GSE14520 (B) datasets. (C) Dot plot showing the dependency scores for SLC27A5 and FDX1 across all tumor cell lines in the Project Achilles/Cancer Dependency Map Portal (DepMap). (D, E) The expression of and correlation between SLC27A5 and FDX1 in collected HCC tissue chip. (F, G) HepG2 (F) and LM-3 (G) cells overexpressing SLC27A5 were subject to qRT-PCR analysis. (H, I) Western blotting using lysates of HepG2 (H) and LM-3 (I) cells after overexpressing SLC27A5.