Research Paper Volume 15, Issue 24 pp 15064—15083
TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer
Figure 11. TMX2 overexpression promotes the migration and invasion of liver cancer cells in vitro. Based on the HPA database, representative immunohistochemical staining of TMX2 in normal and tumor tissues of LIHC (A). Immunohistochemical analysis of TMX2 expression intensity in liver cancer patient (B). Transfection analysis of TMX2 (C). Microscopic observations were recorded at 0, 12, and 24 h after scratching the surface of a confluent layer of the indicated HepG2 and Huh-7 cells (D). Quantitative analysis of wound healing percentage in HepG2 cells (E). Quantitative analysis of wound healing percentage in Huh-7 cells (F). The effects of TMX2 on cell migration and invasion were examined by transwell assays in HepG2 cells (G). Quantitative analysis of cell migration in HepG2 cells (H). Quantitative analysis of cell invasion in HepG-2 cells (I). *p < 0.05, **p < 0.01, ***p < 0.001.