Research Paper Volume 15, Issue 24 pp 14957—14984
A novel oxidative stress-related gene signature as an indicator of prognosis and immunotherapy responses in HNSCC
Figure 2. Univariate Cox and LASSO regression analysis of the DEGs. (A) Forest plot of the top 20 prognostic genes. (B) Confidence interval of each Lambda in the LASSO regression analysis. (C) Trajectory change of LASSO regression independent variables, the abscissa axis indicates the logarithm of the independent variable Lambda, and the vertical axis indicates the coefficient of the independent variable. (D) LASSO regression coefficient of key prognostic genes. The abscissa axis represents coefficients; The vertical axis represents different gene names. (E) Kaplan-Meier curve of SPOCK2 involved in the oxidative stress-related prognostic signatures. (F) Kaplan-Meier curve of SPINK6 involved in the oxidative stress-related prognostic signatures. (G) Kaplan-Meier curve of IFFO2 involved in the oxidative stress-related prognostic signatures. (H) Kaplan-Meier curve of JCHAIN involved in the oxidative stress-related prognostic signatures. (I) Kaplan-Meier curve of AREG involved in the oxidative stress-related prognostic signatures. (J) Kaplan-Meier curve of CES1 involved in the oxidative stress-related prognostic signatures. (K) Kaplan-Meier curve of CSTA involved in the oxidative stress-related prognostic signatures. (L) Kaplan-Meier curve of FDCSP involved in the oxidative stress-related prognostic signatures. (M) Kaplan-Meier curve of PGLYRP4 involved in the oxidative stress-related prognostic signatures.