Research Paper Volume 15, Issue 24 pp 14830—14844

Bioinformatics-based identification and validation of hub genes associated with aging in patients with coronary artery disease

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Figure 4. PPI network and hub genes. (A) PPI network analysis of DEARGs in the GSE12288 dataset. The circles represent genes, the lines represent PPIs between genes, and the results in the circles represent the protein structures. The colors of the lines represent evidence of PPIs. (B) UpSet map obtained by crossing the hub genes generated by the seven algorithms.